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ea0037gp.26.09 | Thyroid – hypothyroidism | ECE2015

No effect of Thr92Ala DIO2 polymorphisms on thyroid parameters, health-related quality of life, and cognitive functioning

Wolffenbuttel Bruce H R , van Loon Hannah C M , Elderson Martin F , van Vliet-Ostaptchouk Jana V , Wouters Hanneke J C M , Kobold Anneke Muller , Links Thera P , Slagter Sandra N , van der Klauw Melanie M

Introduction: The Thr92Ala polymorphism of deiodinase 2 (DIO2) is associated with increased expression in the brain of genes associated with oxidative stress, and may predict favourable response to combination thyroxine (L-T4) plus triiodothyronine (T3) therapy. We examined whether the Thr92Ala polymorphism (rs225014) was associated with differences in thyroid hormone parameters, health-related quality of life (HR-QOL) and cognitive functio...

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Endocrine Abstracts

No effect of Thr92Ala DIO2 polymorphisms on thyroid parameters, health-related quality of life, and cognitive functioning

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